Communications

  • Many NIH-funded research projects rely on vertebrate and invertebrate animals to study fundamentals of biology and physiology, to investigate pathological conditions, to build models of human diseases, and to design novel therapies and translational procedures. ORIP plays a vital role in the area of NIH-funded animal model research by supporting specialized animal research facilities and the...
  • Many NIH-funded research projects rely on vertebrate and invertebrate animals to study fundamentals of biology and physiology, to investigate pathological conditions, to build models of human diseases, and to design novel therapies and translational procedures. ORIP plays a vital role in the area of NIH-funded animal model research by supporting specialized animal research facilities and the...
  • Overview This Funding Opportunity Announcement (FOA) encourages the translation of research discoveries into new treatments for disorders that fall under the mission of NIAAA. The goal is to advance the commercialization of small molecules, natural products or biologics that have shown therapeutic potential for alcohol use disorder or alcohol-related diseases in preclinical testing, by...
  • Overview   This Funding Opportunity Announcement (FOA) encourages the translation of research discoveries into new treatments for disorders that fall under the mission of NIAAA. The goal is to advance the commercialization of small molecules, natural products or biologics that have shown therapeutic potential for alcohol use disorder or alcohol-related diseases in preclinical testing, by...
  • View and Register for all TechRich Events on WBCNA's Website April 2015 1 – DCAA Seminar Series Session #1 8 – DCAA Seminar Series Session #2 15 – DCAA Seminar Series Session #3 22 – DCAA Seminar Series Session #4 22 – SBIR/STTR Class 29 – DCAA Seminar Series Session #5 May 2015 13 – Q3 Ideation Session 29 – Empowering Our Veterans June 2015 3 – Cyber Security Seminar 10 –...
  • The zebrafish is used extensively by NIH funded investigators to examine many aspects of the basic biology of vertebrates and, in the past several years, has become an important model organism for a variety of human diseases. During fiscal year 2013, twenty of the NIH Institutes, Centers and Offices funded approximately 700 grants related to zebrafish research, with an investment totaling...
  • The zebrafish is used extensively by NIH funded investigators to examine many aspects of the basic biology of vertebrates and, in the past several years, has become an important model organism for a variety of human diseases. During fiscal year 2013, twenty of the NIH Institutes, Centers and Offices funded approximately 700 grants related to zebrafish research, with an investment totaling...
  • Despite advances in the treatment of chronic viral hepatitis B and C, the persistence of these and the emergence of other hepatitis viruses continue to remain a public health challenge in the United States. Currently, it is estimated that 3.5 to 5.3 million persons in the United States are afflicted by viral hepatitis. The consequences of acute and chronic viral hepatitis vary, but can be severe...
  • Despite advances in the treatment of chronic viral hepatitis B and C, the persistence of these and the emergence of other hepatitis viruses continue to remain a public health challenge in the United States. Currently, it is estimated that 3.5 to 5.3 million persons in the United States are afflicted by viral hepatitis. The consequences of acute and chronic viral hepatitis vary, but can be severe...
  • Purpose The purpose of this Funding Opportunity Announcement (FOA) is to encourage Small Business Innovation Research (SBIR) grant applications (Phase I [R43] and Phase II [R44]) focused on specific product development activities for radiological/nuclear medical countermeasures leading to Investigational New Drug (IND) or Investigational Device Exemption (IDE) submission packages to the U.S....
  • Overview This Funding Opportunity Announcement (FOA) encourages the translation of research discoveries into new treatments for disorders that fall under the mission of NIAAA.  The goal is to advance the commercialization of small molecules, natural products or biologics that have shown therapeutic potential for alcohol use disorder or alcohol-related diseases in preclinical testing, by...
  • Overview This Funding Opportunity Announcement (FOA) encourages the translation of research discoveries into new treatments for disorders that fall under the mission of NIAAA.  The goal is to advance the commercialization of small molecules, natural products or biologics that have shown therapeutic potential for alcohol use disorder or alcohol-related diseases in preclinical testing, by...
  • Background Twenty-five years after discovery of the gene that causes cystic fibrosis (CF), we now are witnessing the emergence of drug therapies that target the fundamental molecular dysfunctions associated with mutations in the CF transmembrane conductance regulator (CFTR) gene. While these novel therapies offer an exciting prospect for modifying disease outcomes in CF, they may complicate even...
  • A. Overview This FOA is part of a suite of complementary programs to encourage the translation of research discoveries into new treatments for neurological disorders and stroke (http://www.ninds.nih.gov/funding/areas/translational_research/index.htm) that fall under the NINDS mission. The NINDS Cooperative Research to Enable and Advance Translational Enterprises for Devices (CREATE Devices, http...
  • A. Overview This FOA is part of a suite of complementary programs to encourage the translation of research discoveries into new treatments for neurological disorders and stroke (http://www.ninds.nih.gov/funding/areas/translational_research/index.htm) that fall under the NINDS mission. The NINDS Cooperative Research to Enable and Advance Translational Enterprises for Devices (CREATE Devices, http...
  • A. Overview This FOA is part of a suite of complementary programs to encourage the translation of research discoveries into new treatments for neurological disorders and stroke (http://www.ninds.nih.gov/funding/areas/translational_research/index.htm) that fall under the NINDS mission. The NINDS Cooperative Research to Enable and Advance Translational Enterprises for Devices (CREATE Devices, http...
  • Background Recent trends have created a large potential market for breakthrough medical solutions led by tissue engineered medical products.  For example, bioengineered trachea, vascular grafts, and other hollow-organ tissues have made entry into clinical studies, so sophisticated and more standardized bioreactors are critical for testing of complex, neo-organ technologies. ...
  • The SBIR/STTR Programs were recently reauthorized by the United States Congress with the SBIR/STTR Reauthorization Act of 2011(P.L. 112-81).  One change that was made to the SBIR program in this reauthorization was the authority for certain participating federal agencies to ‘issue a Phase II award to a small business concern that did not receive a Phase I award for that research/...
  • Background Recent trends have created a large potential market for breakthrough medical solutions led by tissue engineered medical products.  For example, bioengineered trachea, vascular grafts, and other hollow-organ tissues have made entry into clinical studies, so sophisticated and more standardized bioreactors are critical for testing of complex, neo-organ technologies. ...
  • A. Overview Recent advances in neuroscience offer unprecedented opportunities to discover new treatments for nervous system disorders. However, before a new chemical entity can be tested in a clinical setting, it must undergo a process of chemical optimization to improve potency, selectivity, and drug-like properties, followed by pre-clinical safety testing to meet the standards set by the Food...
  • A. Overview This Funding Opportunity Announcement (FOA) is part of a suite of complementary programs to encourage the translation of research discoveries into new treatments for disorders that fall under the NINDS mission. The NINDS Cooperative Research to Enable and Advance Translational Enterprises for Biotechnology Products and Biologics (CREATE Bio) program is dedicated to biotechnology...
  • A. Overview This Funding Opportunity Announcement (FOA) is part of a suite of complementary programs to encourage the translation of research discoveries into new treatments for disorders that fall under the NINDS mission. The NINDS Cooperative Research to Enable and Advance Translational Enterprises for Biotechnology Products and Biologics (CREATE Bio) program is dedicated to biotechnology...
  • The SBIR/STTR Programs were recently reauthorized by the United States Congress with the SBIR/STTR Reauthorization Act of 2011(P.L. 112-81).  One change that was made to the SBIR program in this reauthorization was the authority for certain participating federal agencies to ‘issue a Phase II award to a small business concern that did not receive a Phase I award for that research/...
  • The Women's Business Center of North Alabama (WBCNA) will now lead the TechRich project, a Small Business Administration (SBA) contract designed to capitalize on existing R...
  • There are important technologies within the biomedical and biobehavioral space that do not require federal regulatory approvals as part of the technology development efforts, but that still require extraordinary time and effort to develop. The purpose of this FOA is to encourage applications for renewals of existing Phase II grants which are supporting research and development of such...
  • Purpose NINDS is committed to advancing diagnostics and treatments for people burdened by neurological diseases and the NINDS Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs have provided the small business community with critical seed funding to support the development of a wide variety of technologies and therapeutics for the treatment of...
  • Background The overarching goal of the SBIR program at the National Institute of Mental Health (NIMH) is to support small businesses to develop technologies that can advance the mission of the Institute, including basic neuroscience research relevant to mental disorders, translational and clinical research of mental disorders, clinical diagnosis or treatment of mental disorders, and...
  • Background The overarching goal of the STTR program at the National Institute of Mental Health (NIMH) is to support small businesses to develop technologies that can advance the mission of the Institute, including basic neuroscience research relevant to mental disorders, translational and clinical research of mental disorders, clinical diagnosis or treatment of mental disorders, and...
  • This Funding Opportunity Announcement (FOA) is encourages Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) that focus on development of technologies in biomedical computing, informatics, and Big Data science. This FOA is coordinated by the NIH Big Data Initiative (BD2K) and the Biomedical Information Science and Technology Initiative (BISTI)...
  • This Funding Opportunity Announcement (FOA) encourages Small Business Technology Transfer (STTR) grant applications from small business concerns (SBCs) that focus on development of technologies in biomedical computing, informatics, and Big Data science. This FOA is coordinated by the NIH Big Data Initiative (BD2K) and the Biomedical Information Science and Technology Initiative (BISTI) committees...
  • Background Recent significant advances in genetics, the basic understanding of physiology, and the pathogenesis of disease coupled with technological advances in areas such as bioinformatics, chemical biology, synthetic chemistry, and protein engineering have provided a rich knowledge base and strong toolbox to identify and pursue new drug targets with the goal of generating new molecular...
  • Diabetes markedly impairs quality of life and shortens lifespan primarily through premature cardiovascular mortality, neuropathy, nephropathy, retinopathy and wound healing compromise. Those complications lead to coronary, cerebral and peripheral artery disease, blindness, renal failure, impaired cognitive function, painful nerve disorders, diabetic foot ulcers and amputation. In addition to its...
  • Background Recent significant advances in genetics, the basic understanding of physiology, and the pathogenesis of disease coupled with technological advances in areas such as bioinformatics, chemical biology, synthetic chemistry, and protein engineering have provided a rich knowledge base and strong toolbox to identify and pursue new drug targets with the goal of generating new molecular...
  • Diabetes markedly impairs quality of life and shortens lifespan primarily through premature cardiovascular mortality, neuropathy, nephropathy, retinopathy and wound healing compromise. Those complications lead to coronary, cerebral and peripheral artery disease, blindness, renal failure, impaired cognitive function, painful nerve disorders, diabetic foot ulcers and amputation. In addition to its...
  • Purpose This Funding Opportunity Announcement seeks small business organizations to develop opioid and adjuvant drug combinations within a single dosage form for treatment of a pain condition. The drug combination should provide improved analgesia when compared with the same dose (morphine equivalents) of opioid monotherapy. Such dosage forms should minimize opioid exposure while optimizing...
  • Purpose This Funding Opportunity Announcement seeks small business organizations to develop opioid and adjuvant drug combinations within a single dosage form for treatment of a pain condition. The drug combination should provide improved analgesia when compared with the same dose (morphine equivalents) of opioid monotherapy. Such dosage forms should minimize opioid exposure while optimizing...
  • By Terry Griffin, Project Manager Huntsville Advanced Defense Technology Cluster Information below describes how federal government agencies and departments have turned to cloud computing. As competition increases for contracts in an austere budget environment, it is essential for small businesses to understand the importance and application of cloud computing. “Cloud computing is...
  • As the Director of Workforce Development at J.F. Drake State Community and Technical College, I am excited to assist your organization meet the challenges associated with today’s workforce initiatives. Drake State is committed to serving its community as the primary provider of workforce development, education and training. Through its Workforce Development Division, the college provides a...
  • The purpose of this Funding Opportunity Announcement (FOA) is to support research using advanced technologies (e.g., bio-chips, microfluidics, and mobile technologies) to develop novel point-of-care (POC) devices and implement existing technologies in clinical settings with a goal to guide diagnostic and therapeutic efforts for the heart, lung, blood, and sleep disorders.  Applicants are...
  • The Science Education Partnership Award (SEPA) program within the Office of Science Education supports and fosters health-related research to build capacity at minority serving institutions and in underserved states, respectively. These programs support a wide variety of biomedical research, including clinical and translational research to reduce health disparities experienced by disadvantaged...
  • The NCCAM Office of Communications is responsible for disseminating CAM information to the public. Therefore applications addressing software development or educational materials and courses (including Continuing Medical Education courses or CD's) will not be considered relevant to the NCCAM SBIR/STTR program. Also not eligible for support are applications seeking to develop cookbooks for...
  • A.     Innovations to accelerate the utilization of personalized medicine: 1.           Biomedical materials and medical devices; 2.           Medical drug, biologics, device and product development; 3.           Therapeutics...
  • Although translational research is supported through the general SBIR/STTR program announcement, the NINDS also has a Cooperative Program in Translational research (PAR-11-296). The NINDS Cooperative Program encourages Phase II and Fast-Track applications that directly address the identification and pre-clinical testing of new therapeutics for neurological disorders. The program will facilitate...
  • NINDS manages the NIH Countermeasures Against Chemical Threats (CounterACT) program. CounterACT supports research and development on new and improved therapeutics or diagnostic technologies to prevent or mitigate the toxic effects from exposure to chemical threats, defined as toxic chemical agents that could be used in a terrorist attack against civilians, or those that could be released at toxic...
  • Funding support is available for the development of educational software and the application of educational technology and tools to facilitate learning of science or health science topics that target K-12 students, families, students from community, tribal, undergraduate colleges and the general public, including health service providers. Topics can range from basic biological, behavioral, social...
  • Studies that promote and advance evidence-based transformations in medical decision-making and health policy; demonstration projects that implement evidence-based, culturally sensitive intervention/disease prevention therapies and diagnostics; and activities designed to build capacity for health disparities research are of high priority. Examples of such studies include, but are not limited to:...
  • The NIMH DAR supports scientific research to understand and alleviate the consequences of HIV infection on the central nervous system, and research to strengthen the provision and outcomes of HIV/AIDS prevention and treatment. High-priority research areas for SBIR/STTR applications are described below. ·       Develop and test novel, non-invasive diagnostic...
  • The Division of Adult Translational Research and Treatment Development plans, supports, and administers programs of research, research training, and resource development aimed at understanding the pathophysiology of mental illness and hastening the translation of behavioral science and neuroscience advances into innovations in clinical care. The Division supports a broad research portfolio, which...
  • The Division of Developmental Translational Research supports programs of research and research training with the ultimate goal of preventing and curing mental disorders that originate in childhood and adolescence. Relevant disorders include mood disorders, anxiety, schizophrenia, autism, ADHD, conduct disorder, eating disorders, obsessive compulsive disorder, and Tourette syndrome. The division...
  • The NHLBI encourages all Phase II applicants to apply to the NIH Commercialization Assistance Program to gain assistance in transferring their products to the marketplace. For additional information on research areas, please contact: Cardiovascular Sciences Albert Lee, Ph.D. Division of Cardiovascular Sciences Advanced Technologies and Surgery Branch 6701 Rockledge Drive, Room 8204...

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